Figure 13. Example cases of xQTL colocalizations in known AD risk genes.

Figure 13. Example cases of xQTL colocalizations in known AD risk genes.#

  • S13a. Example of established AD gene BIN1 across multiple molecular contexts

  • S13b. Example of colocalized variants spanning multiple genes CR1, CR2, YOD1. One variant, rs669515 (MaxVCP=0.755), colocalized with CR2 in DLPFC bulk eQTLs, YOD1 in oligodendrocytes, and CR1 across oligodendrocytes and all three additional bulk cortical eQTLs.

Detailed results can be found in Supplementary Table S1.