Articles

Performing Colocalization using ColocBoost

Tutorials on how to perform multi-trait colocalization analysis using ColocBoost with flexible input data formats.

Input Data Format

Individual Level Data Colocalization

Summary Statistics Data Colocalization

Mixed Data-type and Disease Prioritized Colocalization

Interpretation and Visualization

Tutorials on how to interpret and visualize ColocBoost results.

Interpret ColocBoost Output

Visualization of ColocBoost Results

Colocalization Concepts and Methodology

Educational tutorials on the statistical concepts, assumptions, and algorithms underlying ColocBoost.

Conceptual Framework for Multi-trait Colocalization and ColocBoost

Advanced Colocalization Scenarios with ColocBoost

Animation Example: Proximity Gradient Boosting Algorithm

Advanced Workflows and Special Cases

Practical guidance for specialized data structures, diagnostic scenarios, and extended ColocBoost workflows.

Handling Partial Overlapping Variants across Traits in ColocBoost

Bioinformatics Pipeline for ColocBoost

LD mismatch and LD-free Colocalization

Ambiguous Colocalization from Trait-Specific Effects

Single-trait Fine-mapping with FineBoost