Example Assembled cTWAS Inputs

The assembled cTWAS input list produced by assembleCtwasInputs over a two-LD-block chr22 grid with one gene, ready for estCtwasGroupPriors. Self-contained (no external LD files needed for parameter estimation). Derived from the de-identified protocol_example toy data; all identifiers are synthetic.

Format

A list with the cTWAS input components z_snp, z_gene, weights, region_info, snp_map, LD_map, and the LD / SNP-info loader closures. Each weights entry carries the weights wgt and their variance wgt_var (w'Rw), from which the pipeline computes z_gene, in place of ctwas's per-gene LD matrix R_wgt.

Examples

data(ctwasInputsExample)
names(ctwasInputsExample)
#> [1] "z_snp"              "z_gene"             "weights"           
#> [4] "region_info"        "snp_map"            "LD_map"            
#> [7] "LD_loader_fun"      "snpinfo_loader_fun" "resolvedMethod"