Regional Association Data

S4 container for regional genotype/phenotype/covariate data. Residualized genotypes and phenotypes are computed lazily via accessors.

Slots

genotype_matrix

Numeric matrix (samples x variants) of genotype dosages, with colnames as variant IDs and rownames as sample IDs.

phenotypes

Named list of phenotype matrices (per condition).

covariates

Named list of covariate matrices (per condition).

scale_residuals

Logical, whether to scale residuals.

maf

Named list of MAF vectors (per condition).

region

A GRanges (single range) or NULL.

dropped_samples

Named list of dropped sample vectors.

Y_coordinates

Phenotype coordinates, or NULL.