Abstract container for pre-computed LD statistics. Subclasses provide method-specific representations: eigendecompositions (for LDER/HDL/sHDL) and LD score matrices (for S-LDSC/g-LDSC).
Slots
ld_blocksAn
LDBlocksobject defining the block structure.snp_infoA
data.framewith columnsSNP,CHR,BP,A1,A2, and optionallyMAF.n_refInteger, sample size of the LD reference panel.
in_sampleLogical, whether the LD reference is from the same cohort as the GWAS (affects bias correction).
genomeCharacter string for genome build.