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Construct an LDData from a correlation matrix and/or genotype handle, plus variant metadata as a GRanges.

Usage

LDData(
  correlation = NULL,
  genotype_handle = NULL,
  snp_idx = NULL,
  variants,
  block_metadata,
  n_ref = 0L
)

Arguments

correlation

A correlation matrix, list of matrices, or NULL.

genotype_handle

A GenotypeHandle, list of GenotypeHandles, or NULL.

snp_idx

Integer vector of SNP indices, or NULL.

variants

A GRanges with variant metadata (must have variant_id in mcols, plus A1, A2).

block_metadata

LDBlocks or data.frame with block info.

n_ref

Integer, reference panel sample size.

Value

An LDData object.