Individual level data for 2 traits and 2 causal variants, but the strongest marginal association is not causal

An example dataset with simulated genotypes and traits for 2 traits and 2 common causal variants, but the strongest marginal association is not causal variant.

Usage

Non_Causal_Strongest_Marginal

Format

Non_Causal_Strongest_Marginal

A list with 3 elements

X

List of genotype matrices

Y

List of traits

variant

indices of two causal variants

Source

The Non_Causal_Strongest_Marginal dataset contains 2 simulated phenotypes alongside corresponding genotype matrices. There are two causal variants, but the strongest marginal association is not a causal variant. Due to the file size limitation of CRAN release, this is a subset of simulated data to generate Figure 2b in Cao etc. 2025. See full dataset in colocboost paper repo https://github.com/StatFunGen/colocboost-paper.

See also

Other colocboost_data: Ambiguous_Colocalization, Heterogeneous_Effect, Ind_5traits, Sumstat_5traits, Weaker_GWAS_Effect