Compute SuSiE-RSS TWAS weights — susieRssWeights • pecotmr

Extracts coefficients from an existing SuSiE-RSS fit or fits susieR::susie_rss() from summary statistics and LD.

Usage

susieRssWeights(
  stat,
  LD,
  susieRssFit = NULL,
  retainFit = TRUE,
  methodArgs = list()
)

Arguments

stat: List with components z (z-scores), n (sample sizes).
LD: LD correlation matrix.
susieRssFit: Optional pre-fitted SuSiE-RSS object.
retainFit: If TRUE, stores the fitted object as an attribute.
methodArgs: Named list of additional arguments passed to susieR::susie_rss(). Use this instead of ... to avoid partial matching of short argument names (e.g. L) to the LD parameter.

Value

Numeric vector of variant weights.