Two-stage SuSiE-RSS Fine-mapping — fitSusieInfThenSusieRss • pecotmr

RSS analog of fitSusieInfThenSusie. Fits SuSiE-inf via susieRss first, then initialises standard SuSiE-RSS from the SuSiE-inf result. The single pair of fits can be used both for fine-mapping post-processing and TWAS weight extraction.

Usage

fitSusieInfThenSusieRss(
  z,
  R,
  n,
  args = list(),
  susieInfArgs = list(),
  susieArgs = list(),
  fittedModels = NULL
)

Arguments

z: Numeric vector of z-scores.
R: LD correlation matrix.
n: Sample size (scalar).
args: Default arguments forwarded to both fits.
susieInfArgs: SuSiE-inf-specific overrides.
susieArgs: Standard SuSiE-RSS-specific overrides.
fittedModels: Optional list with pre-fitted $susie and/or $susieInf objects to skip re-fitting.

Value

A list with susie and susieInf fit objects.