LD Statistic (Virtual Base Class)

Abstract container for pre-computed LD statistics. Subclasses provide method-specific representations: eigendecompositions (for LDER/HDL/sHDL) and LD score matrices (for S-LDSC/g-LDSC).

Slots

ldBlocks

An LdBlocks object defining the block structure.

snpInfo

A data.frame with columns SNP, CHR, BP, A1, A2, and optionally MAF.

nRef

Integer, sample size of the LD reference panel.

inSample

Logical, whether the LD reference is from the same cohort as the GWAS (affects bias correction).

genome

Character string for genome build.