Heritability Estimate

Container for univariate heritability estimation results. Holds global, local, and annotation-stratified estimates.

Slots

h2

Numeric, global SNP heritability estimate.

h2_se

Numeric, standard error of global h2.

intercept

Numeric, confounding intercept estimate (NA if method does not estimate one).

intercept_se

Numeric, SE of intercept.

local

A data.frame with per-block local heritability estimates (columns: block_id, h2_local, h2_local_se). NULL if local = FALSE.

enrichment

A data.frame with baseline annotation enrichment estimates (columns: annotation, tau, tau_se, enrichment, enrichment_se, enrichment_p, prop_h2, prop_snps). NULL if unstratified.

tau_blocks

A numeric matrix (n_blocks x n_annotations) of per-block jackknife tau values. Required for Gazal tau_star standardization downstream. NULL if not available (e.g., unstratified analysis).

score_stats

A list with score statistics for candidate annotations, suitable for input to susie_rss. Contains:

z

Numeric vector of z-scores for each candidate annotation

R

Correlation matrix of the score statistics

annotation_names

Character vector of candidate annotation names

NULL if no candidate annotations provided.

method

Character string identifying the estimation method.

n_snps

Integer, number of SNPs used in estimation.

trait_name

Character string for trait identifier.