Heritability Estimate

Container for univariate heritability estimation results. Holds global, local, and annotation-stratified estimates.

Slots

h2

Numeric, global SNP heritability estimate.

h2Se

Numeric, standard error of global h2.

intercept

Numeric, confounding intercept estimate (NA if method does not estimate one).

interceptSe

Numeric, SE of intercept.

local

A data.frame with per-block local heritability estimates (columns: blockId, h2Local, h2LocalSe). NULL if local = FALSE.

enrichment

A data.frame with baseline annotation enrichment estimates (columns: annotation, tau, tauSe, enrichment, enrichmentSe, enrichmentP, propH2, propSnps). NULL if unstratified.

tauBlocks

A numeric matrix (nBlocks x n_annotations) of per-block jackknife tau values. Required for Gazal tauStar standardization downstream. NULL if not available (e.g., unstratified analysis).

scoreStats

A list with score statistics for candidate annotations, suitable for input to susieRss. Contains:

z

Numeric vector of z-scores for each candidate annotation

R

Correlation matrix of the score statistics

annotationNames

Character vector of candidate annotation names

NULL if no candidate annotations provided.

method

Character string identifying the estimation method.

nSnps

Integer, number of SNPs used in estimation.

traitName

Character string for trait identifier.