ROSMAP RNA-seq microglia gene expression QTL#

Religious Orders Study (ROS) or the Rush Memory and Aging Project (MAP) microglia data-set.

Please refer to this document for an overview of the ROSMAP project.

Contact#

Travyse Edwards

Data descriptions#

The ROSMAP monocyte data were downloaded from syn2580853 on Janunary xx, 2023.

• Path on CU cluster /..

I didn’t do cis assocaition for microglia seperately?

Path(s) to fine-mapping with SuSiE RSS model#

Fine-mapping model objects (SuSiE-RSS, .rds) are available in the finemapping models folder (syn69670592).

Path(s) to TWAS models#

Pre-trained TWAS weight models for this context: syn69670600

Quantile TWAS (qTWAS) models: syn69670611

Path(s) to colocalization with SuSiE-coloc / ColocBoost#

Multi-context colocalization models (ColocBoost): syn69670597

AD GWAS–xQTL colocalization results: syn69865816

AD GWAS–xQTL colocalization models: syn69670630