Single-Nucleus RNA-seq Data#
Raw single-nucleus RNA-seq (snRNA-seq) datasets from ROSMAP brain tissue, processed separately by site (CUIMC and MIT) before integration. These datasets underlie the pseudo-bulk eQTL and ISSAC sQTL analyses. → See expression data and splicing data
ROSMAP Datasets#
| Dataset | Site | Donors | Nuclei |
|---|---|---|---|
| ROSMAP snuc CUIMC1 | Columbia University (CUIMC) | 424 | — |
| ROSMAP snuc MIT | MIT | 298 | — |
| ROSMAP snuc Mega | Combined CUIMC + MIT | 530 (192 shared) | 3,177,748 |