https://statfungen.github.io/xqtl-resources/xqtl-data/omics/snATAC/Recent content in Single-Nucleus ATAC-seq Data on FunGen-AD ResourcesHugoen-ushttps://statfungen.github.io/xqtl-resources/xqtl-data/omics/snATAC/ROSMAP_snuc_caQTL/Mon, 01 Jan 0001 00:00:00 +0000https://statfungen.github.io/xqtl-resources/xqtl-data/omics/snATAC/ROSMAP_snuc_caQTL/<h1 id="rosmap-snatac-seq-chromatin-accessibility">ROSMAP snATAC-seq Chromatin Accessibility<a class="anchor" href="#rosmap-snatac-seq-chromatin-accessibility">#</a></h1> <h2 id="summary">Summary<a class="anchor" href="#summary">#</a></h2> <p>Single-nucleus ATAC-seq (snATAC-seq) data from ROSMAP, profiling chromatin accessibility in individual nuclei from DLPFC brain tissue. Includes data from MIT cohort (single-site) and harmonized CUIMC + MIT Multiome ATAC data.</p> <h2 id="dataset-information">Dataset Information<a class="anchor" href="#dataset-information">#</a></h2> <ul> <li><strong>Cohort</strong>: ROSMAP (MIT single-site; CUIMC + MIT harmonized Multiome)</li> <li><strong>Brain region</strong>: Dorsolateral prefrontal cortex (DLPFC)</li> <li><strong>Data type</strong>: Single-nucleus ATAC-seq (snATAC-seq)</li> <li><strong>Cell types</strong>: Multiple brain cell types (neurons, oligodendrocytes, astrocytes, microglia, etc.)</li> <li><strong>Platform</strong>: 10x Genomics Multiome (ATAC+GEX)</li> </ul> <h2 id="omics-data">Omics Data<a class="anchor" href="#omics-data">#</a></h2> <h3 id="chromatin-accessibility-matrices">Chromatin accessibility matrices<a class="anchor" href="#chromatin-accessibility-matrices">#</a></h3> <p>Peak-by-cell count matrices and pseudobulk accessibility profiles available through Synapse.</p>