<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>DNA Methylation Data on FunGen-AD Resources</title><link>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/</link><description>Recent content in DNA Methylation Data on FunGen-AD Resources</description><generator>Hugo</generator><language>en-us</language><atom:link href="https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/index.xml" rel="self" type="application/rss+xml"/><item><title>Knight ADRC brain methylation</title><link>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/Knight_ADRC_brain_methylation/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/Knight_ADRC_brain_methylation/</guid><description>&lt;h1 id="knight-adrc-brain-methylation"&gt;Knight ADRC brain methylation&lt;a class="anchor" href="#knight-adrc-brain-methylation"&gt;#&lt;/a&gt;&lt;/h1&gt;
&lt;h2 id="contact"&gt;Contact&lt;a class="anchor" href="#contact"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;Alexandre Pelletier&lt;/p&gt;
&lt;h2 id="study-metadata"&gt;Study Metadata&lt;a class="anchor" href="#study-metadata"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;&lt;strong&gt;PI&lt;/strong&gt;: Carlos Cruchaga (Washington University in St. Louis)&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Grant numbers&lt;/strong&gt;: R01AG044546, P01AG003991, RF1AG053303, R01AG058501, U01AG058922, RF1AG058501, R01AG057777, P50AG05681, P01AG03991, P01AG026276&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Publication&lt;/strong&gt;: PMID: 38997326&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Genetics publication&lt;/strong&gt;: PMID: 38997326&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Acknowledgement&lt;/strong&gt;: This work was supported by grants from the National Institutes of Health (R01AG044546, P01AG003991, RF1AG053303, R01AG058501, U01AG058922, RF1AG058501 and R01AG057777). The recruitment and clinical characterization of research participants at Washington University were supported by NIH P50 AG05681, P01 AG03991, and P01 AG026276. This work was supported by access to equipment made possible by the Hope Center for Neurological Disorders, and the Departments of Neurology and Psychiatry at Washington University School of Medicine.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Omics data&lt;/strong&gt;: &lt;a href="https://dss.niagads.org/datasets/ng00114/"&gt;ng00114&lt;/a&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Genetics data&lt;/strong&gt;: &lt;a href="https://dss.niagads.org/datasets/ng00127/"&gt;ng00127&lt;/a&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;h2 id="qtl-analysis"&gt;QTL Analysis&lt;a class="anchor" href="#qtl-analysis"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;QTL analysis for this dataset is documented in &lt;a href="https://statfungen.github.io/xqtl-resources/xqtl-data/qtl/mQTL/Knight_ADRC_brain_methylation_qtl/"&gt;../../qtl/mQTL/Knight_ADRC_brain_methylation_qtl.md&lt;/a&gt;.&lt;/p&gt;</description></item><item><title>MSBB brain methylation</title><link>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/MSBB_brain_methylation/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/MSBB_brain_methylation/</guid><description>&lt;h1 id="msbb-brain-methylation"&gt;MSBB brain methylation&lt;a class="anchor" href="#msbb-brain-methylation"&gt;#&lt;/a&gt;&lt;/h1&gt;
&lt;h2 id="contact"&gt;Contact&lt;a class="anchor" href="#contact"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;Alexandre Pelletier&lt;/p&gt;
&lt;h2 id="qtl-analysis"&gt;QTL Analysis&lt;a class="anchor" href="#qtl-analysis"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;QTL analysis for this dataset is documented in &lt;a href="https://statfungen.github.io/xqtl-resources/xqtl-data/qtl/mQTL/MSBB_brain_methylation_qtl/"&gt;../../qtl/mQTL/MSBB_brain_methylation_qtl.md&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;Flagship paper analyses:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Fine-mapping (fSuSiE/SuSiE-RSS): &lt;a href="https://www.synapse.org/Synapse:syn69670592"&gt;syn69670592&lt;/a&gt;&lt;/li&gt;
&lt;li&gt;Pairwise colocalization (SuSiE-coloc): &lt;a href="https://www.synapse.org/Synapse:syn69670597"&gt;syn69670597&lt;/a&gt;&lt;/li&gt;
&lt;li&gt;AD GWAS–xQTL colocalization results: &lt;a href="https://www.synapse.org/Synapse:syn69865816"&gt;syn69865816&lt;/a&gt;&lt;/li&gt;
&lt;li&gt;AD GWAS–xQTL colocalization models: &lt;a href="https://www.synapse.org/Synapse:syn69670630"&gt;syn69670630&lt;/a&gt;&lt;/li&gt;
&lt;/ul&gt;</description></item><item><title>ROSMAP DLPFC methylation</title><link>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/ROSMAP_DLPFC_methylation/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://statfungen.github.io/xqtl-resources/xqtl-data/omics/methylation/ROSMAP_DLPFC_methylation/</guid><description>&lt;h1 id="rosmap-dlpfc-methylation"&gt;ROSMAP DLPFC methylation&lt;a class="anchor" href="#rosmap-dlpfc-methylation"&gt;#&lt;/a&gt;&lt;/h1&gt;
&lt;p&gt;Religious Orders Study (ROS) or the Rush Memory and Aging Project (MAP) DLPFC methylation data-set.&lt;/p&gt;
&lt;p&gt;Please refer to &lt;a href="https://statfungen.github.io/xqtl-resources/xqtl-data/study_info/ROSMAP/"&gt;this document&lt;/a&gt; for an overview of the ROSMAP project.&lt;/p&gt;
&lt;h2 id="contact"&gt;Contact&lt;a class="anchor" href="#contact"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;Alexandre Pelletier, Jiajun Tao&lt;/p&gt;
&lt;h2 id="study-overview"&gt;Study Overview&lt;a class="anchor" href="#study-overview"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;Grant number : U01AG046152, R01AG048015, U01AG061356, R01AG15819, U01AG061359&lt;/li&gt;
&lt;li&gt;Publication : PMID: 30084846&lt;/li&gt;
&lt;li&gt;Acknowledgement : Study data were generated from postmortem brain tissue provided by the Religious Orders Study and Rush Memory and Aging Project (ROSMAP) cohort at Rush Alzheimer&amp;rsquo;s Disease Center, Rush University Medical Center, Chicago.&lt;/li&gt;
&lt;li&gt;Data Citation : Omics data: &lt;a href="https://www.synapse.org/Synapse:syn3157275"&gt;syn3157275&lt;/a&gt;; Genetics data: &lt;a href="https://dss.niagads.org/datasets/ng00067/"&gt;ng00067&lt;/a&gt;&lt;/li&gt;
&lt;li&gt;Genetics Publication : PMID: 40407102&lt;/li&gt;
&lt;li&gt;PI : David A. Bennett (Rush University Medical Center, Chicago, IL, USA)&lt;/li&gt;
&lt;/ul&gt;
&lt;h2 id="qtl-analysis"&gt;QTL Analysis&lt;a class="anchor" href="#qtl-analysis"&gt;#&lt;/a&gt;&lt;/h2&gt;
&lt;p&gt;QTL analysis for this dataset is documented in &lt;a href="https://statfungen.github.io/xqtl-resources/xqtl-data/qtl/mQTL/ROSMAP_DLPFC_methylation_qtl/"&gt;../../qtl/mQTL/ROSMAP_DLPFC_methylation_qtl.md&lt;/a&gt;.&lt;/p&gt;</description></item></channel></rss>